API reference
Lubiprostone
- CAS number
- 333963-40-9
- Molecular formula
- C20H32F2O5
- Molecular weight
- 390.5 g/mol
About this molecule
Lubiprostone is a bicyclic fatty acid derived from prostaglandin E1 and a chloride channel activator with laxative activity. Upon intake, lubiprostone specifically binds to and activates the type 2 chloride channel (ClC-2) in the apical membrane of the gastrointestinal epithelium. This produces an efflux of chloride ions, thereby drawing water into the gastrointestinal lumen. The resulting increased amounts of intestinal fluid soften the stool, increase motility, and improve bowel movements.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-yl]heptanoic acid
- InChIKey
- WGFOBBZOWHGYQH-MXHNKVEKSA-N
- SMILES
- CCCCC([C@]1(CC[C@H]2[C@H](O1)CC(=O)[C@@H]2CCCCCCC(=O)O)O)(F)F
- PubChem CID
- 157920
Also known as
Lubiprostone · Lubiprostone hemiketal · lubiprostona · lubiprostonum · Amitza · A06AX03 · 603-977-7 · Amitiza
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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