API reference
Mafenide acetate
- CAS number
- 13009-99-9
- Molecular formula
- C9H14N2O4S
- Molecular weight
- 246.29 g/mol
About this molecule
Mafenide Acetate is the acetate salt form of mafenide, a synthetic sulfonamide analog of para-aminobenzoic acid (PABA) with topical anti-infective activity. Mafenide acetate competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, thereby interferes with normal folic acid metabolism. As a result, de novo synthesis of pyrimidines, which requires folate metabolites, is impeded and subsequently DNA synthesis is affected. Mafenide acetate is bacteriostatic against many gram-negative and gram-positive organisms, including Pseudomonas aeruginosa and certain strains of anaerobes.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- acetic acid;4-(aminomethyl)benzenesulfonamide
- InChIKey
- UILOTUUZKGTYFQ-UHFFFAOYSA-N
- SMILES
- CC(=O)O.C1=CC(=CC=C1CN)S(=O)(=O)N
- PubChem CID
- 25590
Also known as
MAFENIDE ACETATE · Sulfamilon · Benzenesulfonamide, 4-(aminomethyl)-, monoacetate · alpha-Amino-p-toluenesulfonamide monoacetate · 4-(Aminomethyl)benzenesulfonamide monoacetate · 4-(AMINOMETHYL)BENZENESULFONAMIDE ACETATE · Mafatate · Maphenide acetate
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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