API reference

Mannitol

CAS number
69-65-8
Molecular formula
C6H14O6
Molecular weight
182.17 g/mol
Mannitol — 2D structure
2D structure (PubChem)

About this molecule

Mannitol is a naturally occurring alcohol found in fruits and vegetables and used as an osmotic diuretic. Mannitol is freely filtered by the glomerulus and poorly reabsorbed from the renal tubule, thereby causing an increase in osmolarity of the glomerular filtrate. An increase in osmolarity limits tubular reabsorption of water and inhibits the renal tubular reabsorption of sodium, chloride, and other solutes, thereby promoting diuresis. In addition, mannitol elevates blood plasma osmolarity, resulting in enhanced flow of water from tissues into interstitial fluid and plasma.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
InChIKey
FBPFZTCFMRRESA-KVTDHHQDSA-N
SMILES
C([C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)O
Other CAS numbers recorded
87-78-5 · 133-43-7 · 85085-15-0
PubChem CID
6251

Also known as

D-mannitol · mannitol · Mannite · Osmitrol · Manna sugar · Cordycepic acid · Diosmol · Mannigen

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