API reference
Melatonin
- CAS number
- 73-31-4
- Molecular formula
- C13H16N2O2
- Molecular weight
- 232.28 g/mol

About this molecule
Melatonin is a hormone involved in sleep regulatory activity, and a tryptophan-derived neurotransmitter, which inhibits the synthesis and secretion of other neurotransmitters such as dopamine and GABA. Melatonin is synthesized from serotonin intermediate in the pineal gland and the retina where the enzyme 5-hydroxyindole-O-methyltransferase, that catalyzes the last step of synthesis, is found. This hormone binds to and activates melatonin receptors and is involved in regulating the sleep and wake cycles. In addition, melatonin possesses antioxidative and immunoregulatory properties via regulating other neurotransmitters.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
- InChIKey
- DRLFMBDRBRZALE-UHFFFAOYSA-N
- SMILES
- CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC
- Other CAS numbers recorded
- 8041-44-9
- PubChem CID
- 896
Also known as
Melatonin · Melatonine · N-Acetyl-5-methoxytryptamine · Circadin · 5-Methoxy-N-acetyltryptamine · Melatol · Melovine · N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide
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