API reference

Melatonin

CAS number
73-31-4
Molecular formula
C13H16N2O2
Molecular weight
232.28 g/mol
Melatonin — 2D structure
2D structure (PubChem)

About this molecule

Melatonin is a hormone involved in sleep regulatory activity, and a tryptophan-derived neurotransmitter, which inhibits the synthesis and secretion of other neurotransmitters such as dopamine and GABA. Melatonin is synthesized from serotonin intermediate in the pineal gland and the retina where the enzyme 5-hydroxyindole-O-methyltransferase, that catalyzes the last step of synthesis, is found. This hormone binds to and activates melatonin receptors and is involved in regulating the sleep and wake cycles. In addition, melatonin possesses antioxidative and immunoregulatory properties via regulating other neurotransmitters.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
InChIKey
DRLFMBDRBRZALE-UHFFFAOYSA-N
SMILES
CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC
Other CAS numbers recorded
8041-44-9
PubChem CID
896

Also known as

Melatonin · Melatonine · N-Acetyl-5-methoxytryptamine · Circadin · 5-Methoxy-N-acetyltryptamine · Melatol · Melovine · N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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