API reference
MEMANTINE HCl
- CAS number
- 41100-52-1
- Molecular formula
- C12H22ClN
- Molecular weight
- 215.76 g/mol
About this molecule
Memantine Hydrochloride is the hydrochloride salt of memantine, a low-affinity, voltage-dependent, noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. Memantine binds to and inhibits cation channels of glutamanergic NMDA receptors located in the central nervous system (CNS), preventing the prolonged influx of calcium ions and the associated neuronal excitotoxicity, and thereby potentially enhancing cognitive function. Memantine is also a 5-hydroxytryptamine type 3 (5HT3) receptor and nicotinic receptor antagonist.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 3,5-dimethyladamantan-1-amine;hydrochloride
- InChIKey
- LDDHMLJTFXJGPI-UHFFFAOYSA-N
- SMILES
- CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl
- PubChem CID
- 181458
Also known as
MEMANTINE HYDROCHLORIDE · Memantine HCL · 3,5-dimethyladamantan-1-amine hydrochloride · 3,5-Dimethyl-1-adamantanamine hydrochloride · Akatinol · Namenda XR · Memary · Memantine Merz
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