API reference
Methimazole
- CAS number
- 60-56-0
- Molecular formula
- C4H6N2S
- Molecular weight
- 114.17 g/mol
About this molecule
Methimazole is a thioamide inhibitor of the enzyme thyroid peroxidase (TPO), with antithyroid activity. Upon administration, methimazole inhibits the metabolism of iodide and the iodination of tyrosine residues in the thyroid hormone precursor thyroglobulin by TPO; this prevents the synthesis of the thyroid hormones triiodothyronine (T3) and thyroxine (T4).
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 3-methyl-1H-imidazole-2-thione
- InChIKey
- PMRYVIKBURPHAH-UHFFFAOYSA-N
- SMILES
- CN1C=CNC1=S
- Other CAS numbers recorded
- 85916-84-3 · 223768-14-7
- PubChem CID
- 1349907
Also known as
methimazole · thiamazole · Tapazole · 1-Methyl-1H-imidazole-2-thiol · Methimazol · 1-Methylimidazole-2-thiol · Mercazolyl · Thiamazol
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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