API reference
Methohexital
- CAS number
- 151-83-7
- Molecular formula
- C14H18N2O3
- Molecular weight
- 262.3 g/mol
About this molecule
Methohexital is only found in individuals that have used or taken this drug. It is an intravenous anesthetic with a short duration of action that may be used for induction of anesthesia. Methohexital binds at a distinct binding site associated with a Cl<sup>-</sup> ionopore at the GABA<sub>A</sub> receptor, increasing the duration of time for which the Cl<sup>-</sup> ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged.
Source: Toxin and Toxin Target Database (T3DB), via PubChem.
Identifiers
- IUPAC name
- 5-hex-3-yn-2-yl-1-methyl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
- InChIKey
- NZXKDOXHBHYTKP-UHFFFAOYSA-N
- SMILES
- CCC#CC(C)C1(C(=O)NC(=O)N(C1=O)C)CC=C
- Other CAS numbers recorded
- 18652-93-2
- PubChem CID
- 9034
Also known as
Methohexitone · Methodrexitone · Metohexital · Methohexitalum · Metoesital · 5-Allyl-5-(3-hexyn-2-yl)-1-methylbarbituric acid · (+-)-5-Allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acid · Methohexital, Monosodium Salt
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