API reference
Methsuximide
- CAS number
- 77-41-8
- Molecular formula
- C12H13NO2
- Molecular weight
- 203.24 g/mol

About this molecule
Methsuximide is a succinimide with anticonvulsant properties. Although the exact mechanism of action of methsuximide is unclear, it is thought to increase the seizure threshold and suppress the paroxysmal three-cycle-per-second spike-and-wave pattern seen with absence (petit mal) seizures. The frequency of attacks is reduced by depression of nerve transmission in the motor cortex and elevation of the threshold of the CNS to convulsive stimuli, probably due to direct modification of membrane function in excitable cells and/or alteration of chemically mediated neurotransmission.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione
- InChIKey
- AJXPJJZHWIXJCJ-UHFFFAOYSA-N
- SMILES
- CC1(CC(=O)N(C1=O)C)C2=CC=CC=C2
- PubChem CID
- 6476
Also known as
Mesuximide · Celontin · 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione · Methsuximid · Metsuccimide · Mesuximidum · mesuximid · alpha-Methylphensuximide
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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