API reference

Metolazone

CAS number
17560-51-9
Molecular formula
C16H16ClN3O3S
Molecular weight
365.8 g/mol
Metolazone — 2D structure
2D structure (PubChem)

About this molecule

Metolazone is a quinazoline that consists of 1,2,3,4-tetrahydroquinazolin-4-one bearing additional methyl, 2-tolyl, sulfamyl and chloro substituents at positions 2, 3, 6 and 7 respectively. A quinazoline diuretic, with properties similar to thiazide diuretics. It has a role as a diuretic, an antihypertensive agent and an ion transport inhibitor. It is a sulfonamide, an organochlorine compound and a member of quinazolines.

Source: ChEBI, via PubChem.

Identifiers

IUPAC name
7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2-dihydroquinazoline-6-sulfonamide
InChIKey
AQCHWTWZEMGIFD-UHFFFAOYSA-N
SMILES
CC1NC2=CC(=C(C=C2C(=O)N1C3=CC=CC=C3C)S(=O)(=O)N)Cl
Other CAS numbers recorded
56436-32-9 · 56436-31-8
PubChem CID
4170

Also known as

metolazone · Zaroxolyn · Diulo · Mykrox · Oldren · Metenix · Metalozone · Metolazona

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