API reference
Metyrosine
- CAS number
- 672-87-7
- Molecular formula
- C10H13NO3
- Molecular weight
- 195.21 g/mol
About this molecule
Alpha-methyl-L-tyrosine is an L-tyrosine derivative that consists of L-tyrosine bearing an additional methyl substituent at position 2. An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. It has a role as an antihypertensive agent and an EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor. It is a L-tyrosine derivative and a non-proteinogenic L-alpha-amino acid.
Source: ChEBI, via PubChem.
Identifiers
- IUPAC name
- (2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid
- InChIKey
- NHTGHBARYWONDQ-JTQLQIEISA-N
- SMILES
- C[C@](CC1=CC=C(C=C1)O)(C(=O)O)N
- PubChem CID
- 441350
Also known as
Metirosine · Demser · Metirosina · (2S)-2-amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid · (S)-alpha-Methyltyrosine · L-alpha-Methyltyrosine · Metirosinum · (-)-alpha-Methyl-L-tyrosine
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