API reference
Midazolam
- CAS number
- 59467-70-8
- Molecular formula
- C18H13ClFN3
- Molecular weight
- 325.8 g/mol
About this molecule
Midazolam is a short-acting benzodiazepine derivative with an imidazole structure and with anxiolytic, amnestic, hypnotic, anticonvulsant and sedative properties. Midazolam exerts its effect by binding to the benzodiazepine receptor at the gamma-aminobutyric acid (GABA) receptor-chloride ionophore complex in the central nervous system (CNS). This leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA in the CNS. Midazolam may also interfere with the reuptake of GABA, thereby causing accumulation of GABA in the synaptic cleft.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
- InChIKey
- DDLIGBOFAVUZHB-UHFFFAOYSA-N
- SMILES
- CC1=NC=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4F
- PubChem CID
- 4192
Also known as
midazolam · Buccolam · Midazolamum · mezolam · Nayzilam · Midazolam civ · USL261 · USL-261
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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