API reference
MIDODRINE HCl
- CAS number
- 43218-56-0
- Molecular formula
- C12H19ClN2O4
- Molecular weight
- 290.74 g/mol
About this molecule
Midodrine Hydrochloride is the hydrochloride salt form of midodrine, a direct-acting prodrug and sympathomimetic agent with antihypotensive properties. Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to an elevation of blood pressure. Desglymidodrine diffuses poorly across the blood-brain barrier, and is therefore not associated with effects on the central nervous system.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide;hydrochloride
- InChIKey
- MGCQZNBCJBRZDT-UHFFFAOYSA-N
- SMILES
- COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O.Cl
- Other CAS numbers recorded
- 3092-17-9
- PubChem CID
- 18340
Also known as
MIDODRINE HYDROCHLORIDE · Midodrine HCL · Pro-Amatine · ProAmatine · Hipertan · Amatine · Orvaten · Gutron
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
Tell us the grade, the quantity and the market.
Send the molecule or ingredient, the specification and the destination. We reply from Tehran with the questions, the documents and the next step.