API reference

Mifepristone

CAS number
84371-65-3
Molecular formula
C29H35NO2
Molecular weight
429.6 g/mol
Mifepristone — 2D structure
2D structure (PubChem)

About this molecule

Mifepristone, also known as RU-486, is a potent synthetic steroidal antiprogesterone which is used as a single dose in combination with misoprostol, a prostaglandin analogue, to induce medical abortion. Mifepristone with misoprostol have not been associated with serum enzyme elevations or with clinically apparent liver injury. Mifepristone alone, without misoprostol, is also approved as therapy of Cushing syndrome where it is given in a higher dose and for extended periods. Long term higher doses of mifepristone have been linked to a low rate of serum enzyme elevations during therapy and rare instances of clinically apparent liver injury.

Source: LiverTox, via PubChem.

Identifiers

IUPAC name
(8S,11R,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
InChIKey
VKHAHZOOUSRJNA-GCNJZUOMSA-N
SMILES
CC#C[C@@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)C5=CC=C(C=C5)N(C)C)C)O
Other CAS numbers recorded
122742-25-0 · 83203-42-3
PubChem CID
55245

Also known as

mifepristone · Mifegyne · Mifeprex · RU-486 · Korlym · RU 486 · Mifepristona · Mifepristonum

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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