API reference
MITOXANTRONE HCl
- CAS number
- 70476-82-3
- Molecular formula
- C22H30Cl2N4O6
- Molecular weight
- 517.4 g/mol
About this molecule
Mitoxantrone Hydrochloride is the hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione;dihydrochloride
- InChIKey
- ZAHQPTJLOCWVPG-UHFFFAOYSA-N
- SMILES
- C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO.Cl.Cl
- PubChem CID
- 51082
Also known as
Mitoxantrone hydrochloride · Mitoxantrone dihydrochloride · Onkotrone · Mitozantrone hydrochloride · CL 232,315 · Mitroxone · Neotalem · Pralifan
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
Tell us the grade, the quantity and the market.
Send the molecule or ingredient, the specification and the destination. We reply from Tehran with the questions, the documents and the next step.