API reference
Modafinil
- CAS number
- 68693-11-8
- Molecular formula
- C15H15NO2S
- Molecular weight
- 273.4 g/mol

About this molecule
Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. The prexin neuron activation is associated with psychoactivation and euphoria. The exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the reuptake of dopamine by binding to the dopamine reuptake pump, and lead to an increase in extracellular dopamine. Modafinil activates glutamatergic circuits while inhibiting GABA.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- 2-benzhydrylsulfinylacetamide
- InChIKey
- YFGHCGITMMYXAQ-UHFFFAOYSA-N
- SMILES
- C1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC(=O)N
- Other CAS numbers recorded
- 112111-49-6
- PubChem CID
- 4236
Also known as
modafinil · Provigil · Modiodal · 2-(Benzhydrylsulfinyl)acetamide · 2-benzhydrylsulfinylacetamide · modaphonil · Modafinilo · Modafinilum
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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