API reference
Monomethyl fumarate
- CAS number
- 2756-87-8
- Molecular formula
- C5H6O4
- Molecular weight
- 130.1 g/mol
About this molecule
Monomethyl fumarate is a dicarboxylic acid monoester resulting from the formal condensation of one of the carboxy groups of fumaric acid with methanol. Is is a metabolite of dimethyl fumarate and used for the the treatment of patients with relapsing multiple sclerosis (MS). It also induces the NFE2L2 (Nrf2) transcription factor by binding to KEAP1. It has a role as an antioxidant, a drug metabolite and an immunomodulator. It is a methyl ester, a dicarboxylic acid monoester and an enoate ester. It is functionally related to a fumaric acid.
Source: ChEBI, via PubChem.
Identifiers
- IUPAC name
- (E)-4-methoxy-4-oxobut-2-enoic acid
- InChIKey
- NKHAVTQWNUWKEO-NSCUHMNNSA-N
- SMILES
- COC(=O)/C=C/C(=O)O
- Other CAS numbers recorded
- 44836-34-2
- PubChem CID
- 5369209
Also known as
Monomethyl fumarate · Fumaric acid monomethyl ester · Bafiertam · methylhydrogenfumarate · 220-412-6 · Methyl Fumarate · monomethylfumarate · 4-methoxy-4-oxobut-2-enoic acid
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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