API reference
Mycophenolate sodium
- CAS number
- 37415-62-6
- Molecular formula
- C17H19NaO6
- Molecular weight
- 342.3 g/mol
About this molecule
Mycophenolate Sodium is the sodium salt form of mycophenolic acid (MPA), with immunosuppressing activity. In vivo, the active molecule MPA reversibly inhibits inosine monophosphate dehydrogenase (IMPDH) which is needed for guanine monophosphate synthesis and stops the proliferation of B and T lymphocytes. Relative to other cell types, lypmocytes are highly dependent on salvage and de novo synthesis of guanine nucleotides, thus making these cells prone to MPA cytotoxicity.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- sodium (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
- InChIKey
- DOZYTHNHLLSNIK-JOKMOOFLSA-M
- SMILES
- CC1=C2COC(=O)C2=C(C(=C1OC)C/C=C(\C)/CCC(=O)[O-])O.[Na+]
- PubChem CID
- 23665584
Also known as
MYCOPHENOLATE SODIUM · Sodium mycophenolate · Mycophenolic acid monosodium salt · Mycophenolic acid sodium salt · ERL 080 · Sodium mycophenalate · Ceptava · ERL 080A
Related entries in the range
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