API reference
Nafcillin sodium
- CAS number
- 985-16-0
- Molecular formula
- C21H21N2NaO5S
- Molecular weight
- 436.5 g/mol
About this molecule
Nafcillin Sodium Anhydrous is the anhydrous form of the sodium salt of nafcillin, a narrow-spectrum beta-lactamase-resistant penicillin with antibacterial activity. Nafcillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- sodium (2S,5R,6R)-6-[(2-ethoxynaphthalene-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
- InChIKey
- AYAPZOUDXCDGIF-FRFVDRIFSA-M
- SMILES
- CCOC1=C(C2=CC=CC=C2C=C1)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)[O-].[Na+]
- Other CAS numbers recorded
- 7177-50-6
- PubChem CID
- 23667630
Also known as
NAFCILLIN SODIUM · Sodium nafcillin · Nafcillin sodium anhydrous · Nallpen · Unipen · 6-(2-Ethoxy-1-naphthamido)penicillin sodium · Nallpen In Plastic Container · Sodium 6-(2-ethoxy-1-naphthamido)penicillanate
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