API reference
NALOXONE HCl
- CAS number
- 357-08-4
- Molecular formula
- C19H22ClNO4
- Molecular weight
- 363.8 g/mol
About this molecule
Naloxone Hydrochloride is the hydrochloride salt of naloxone, a thebaine derivate with opioid antagonist activity. Naloxone binds to opioid receptors in the CNS in a competitive manner, reversing or inhibiting characteristic opioid effects, including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia, and physical dependence. This agent binds to mu-opioid receptors with a high affinity, and a lesser degree to kappa- and gamma-opioid receptors.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride
- InChIKey
- RGPDIGOSVORSAK-STHHAXOLSA-N
- SMILES
- C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O.Cl
- PubChem CID
- 5464092
Also known as
Naloxone hydrochloride · Naloxone HCl · Evzio · REZENOPY · RIVIVE · KLOXXADO · Anhydrous naloxone hydrochloride · Naloxone hydrochloride anhydrous
Related entries in the range
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