API reference
NALTREXONE HCl
- CAS number
- 16676-29-2
- Molecular formula
- C20H24ClNO4
- Molecular weight
- 377.9 g/mol
About this molecule
Naltrexone Hydrochloride is the hydrochloride salt of naltrexone, a noroxymorphone derivative with competitive opioid antagonistic activity. Naltrexone and its metabolite 6-beta-naltrexol reverse the effects of opioids by binding to various opioid receptors in the central nervous system CNS), including the mu-, kappa- and gamma-opioid receptors; opioid effects of analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia, and physical dependence are inhibited. Naltrexone is longer-acting and more potent compared to naloxone.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride
- InChIKey
- RHBRMCOKKKZVRY-ITLPAZOVSA-N
- SMILES
- C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O.Cl
- PubChem CID
- 5485201
Also known as
Naltrexone hydrochloride · Naltrexone Hcl · Depade · naltrexone.HCl · Trexonil · N-Cyclopropylmethyl-noroxymorphone hydrochloride · Naltrexone hydrochloride (USP) · TROXYCA COMPONENT NALTREXONE HYDROCHLORIDE
Related entries in the range
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