API reference
Nateglinide
- CAS number
- 105816-04-4
- Molecular formula
- C19H27NO3
- Molecular weight
- 317.4 g/mol
About this molecule
Nateglinide is a phenylalanine derivative of the meglitinide class of agents with hypoglycemic activity. Nateglinide, compared to repaglitinide, binds with a higher affinity to the SUR1 subunit and with a faster onset of action and a shorter duration of action. This agent is metabolized by the cytochrome P450 isoenzyme CYP2C9, and, to a lesser extent, by CYP3A4. The parent drug and metabolites are mainly excreted in the urine and its half-life is about 1.5 hours.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (2R)-3-phenyl-2-[(4-propan-2-ylcyclohexanecarbonyl)amino]propanoic acid
- InChIKey
- OELFLUMRDSZNSF-OFLPRAFFSA-N
- SMILES
- CC(C)C1CCC(CC1)C(=O)N[C@H](CC2=CC=CC=C2)C(=O)O
- Other CAS numbers recorded
- 105816-06-6 · 105746-37-0
- PubChem CID
- 5311309
Also known as
nateglinide · Starlix · Starsis · senaglinide · Fastic · Trazec · D-Nateglinide · DJN 608
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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