API reference

Niacin

CAS number
59-67-6
Molecular formula
C6H5NO2
Molecular weight
123.11 g/mol
Niacin — 2D structure
2D structure (PubChem)

About this molecule

Niacin is a water-soluble vitamin belonging to the vitamin B family, which occurs in many animal and plant tissues, with antihyperlipidemic activity. Niacin is converted to its active form niacinamide, which is a component of the coenzymes nicotinamide adenine dinucleotide (NAD) and its phosphate form, NADP. These coenzymes play an important role in tissue respiration and in glycogen, lipid, amino acid, protein, and purine metabolism. Although the exact mechanism of action by which niacin lowers cholesterol is not fully understood, it may act by inhibiting the synthesis of very low density lipoproteins (VLDL), inhibiting the release of free fatty acids from adipose tissue, increasing lipoprotein lipase activity, and reducing the hepatic synthesis of VLDL-C and LDL-C.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
pyridine-3-carboxylic acid
InChIKey
PVNIIMVLHYAWGP-UHFFFAOYSA-N
SMILES
C1=CC(=CN=C1)C(=O)O
Other CAS numbers recorded
101113-41-1
PubChem CID
938

Also known as

nicotinic acid · niacin · Pyridine-3-carboxylic acid · 3-pyridinecarboxylic acid · 3-Carboxypyridine · Akotin · wampocap · Apelagrin

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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