API reference

Niclosamide

CAS number
50-65-7
Molecular formula
C13H8Cl2N2O4
Molecular weight
327.12 g/mol
Niclosamide — 2D structure
2D structure (PubChem)

About this molecule

Niclosamide is a secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections. It has a role as an anticoronaviral agent, a piscicide, a molluscicide, an antiparasitic agent, an anthelminthic drug, an apoptosis inducer and a STAT3 inhibitor. It is a secondary carboxamide, a member of benzamides, a C-nitro compound, a member of salicylanilides and a member of monochlorobenzenes. It is functionally related to a 5-chlorosalicylic acid.

Source: ChEBI, via PubChem.

Identifiers

IUPAC name
5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
InChIKey
RJMUSRYZPJIFPJ-UHFFFAOYSA-N
SMILES
C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O
PubChem CID
4477

Also known as

niclosamide · 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide · Niclocide · Cestocid · Mansonil · Phenasal · Tredemine · Vermitid

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