API reference

Nifedipine

CAS number
21829-25-4
Molecular formula
C17H18N2O6
Molecular weight
346.3 g/mol
Nifedipine — 2D structure
2D structure (PubChem)

About this molecule

Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to [nicardipine]. Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972. Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer durations of action. The most popular of the third generation dihydropyridines is [amlodipine]. Nifedipine was granted FDA approval on 31 December 1981.

Source: DrugBank, via PubChem.

Identifiers

IUPAC name
dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
InChIKey
HYIMSNHJOBLJNT-UHFFFAOYSA-N
SMILES
CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
Other CAS numbers recorded
193689-82-6 · 101539-70-2 · 915092-63-6
PubChem CID
4485

Also known as

nifedipine · Procardia · Adalat · Procardia XL · Citilat · Oxcord · Adalat CC · Fenihidine

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