API reference
Nilutamide
- CAS number
- 63612-50-0
- Molecular formula
- C12H10F3N3O4
- Molecular weight
- 317.22 g/mol
About this molecule
Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors). Consequently, Nilutamide blocks the action of androgens of adrenal and testicular origin that stimulate the growth of normal and malignant prostatic tissue. Prostate cancer is mostly androgen-dependent and can be treated with surgical or chemical castration. To date, antiandrogen monotherapy has not consistently been shown to be equivalent to castration.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
- InChIKey
- XWXYUMMDTVBTOU-UHFFFAOYSA-N
- SMILES
- CC1(C(=O)N(C(=O)N1)C2=CC(=C(C=C2)[N+](=O)[O-])C(F)(F)F)C
- PubChem CID
- 4493
Also known as
nilutamide · Anandron · Nilandron · Nilutamida · Nilutamidum · Anadron · L02BB02 · 624-700-6
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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