API reference
Nintedanib esylate
- CAS number
- 656247-18-6
- Molecular formula
- C33H39N5O7S
- Molecular weight
- 649.8 g/mol
About this molecule
Nintedanib esylate is an organosulfonate salt obtained by combining nintedanib with one molar equivalent of ethanesulfonic acid. A kinase inhibitor used for the treatment of idiopathic pulmonary fibrosis and cancer. It has a role as an antifibrotic agent, an antineoplastic agent, a tyrosine kinase inhibitor, an angiogenesis inhibitor, a fibroblast growth factor receptor antagonist and a vascular endothelial growth factor receptor antagonist. It contains a nintedanib(1+).
Source: ChEBI, via PubChem.
Identifiers
- IUPAC name
- ethanesulfonic acid;methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate
- InChIKey
- ZNMRDZZRAFJOKY-UHFFFAOYSA-N
- SMILES
- CCS(=O)(=O)O.CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O
- PubChem CID
- 135476717
Also known as
Nintedanib esylate · Nintedanib Ethanesulfonate Salt · Nintedanib ethanesulfonate · OFEV · Nintedanib Esilate · Nintedanib esylate (USAN) · Ofev (TN) · Nintedanib ethanesulfonate (JAN)
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
Tell us the grade, the quantity and the market.
Send the molecule or ingredient, the specification and the destination. We reply from Tehran with the questions, the documents and the next step.