API reference
Nitisinone
- CAS number
- 104206-65-7
- Molecular formula
- C14H10F3NO5
- Molecular weight
- 329.23 g/mol
About this molecule
Nitisinone is an inhibitor of the tyrosine catabolism that is used to treat hereditary tyrosinemia, type 1, in which accumulation of intermediates of tyrosine metabolism causes severe and progressive hepatic and renal injury. Nitisinone has been associated with mild, transient serum aminotransferase elevations, but has not been linked to instances of clinically apparent acute liver injury or jaundice.
Source: LiverTox, via PubChem.
Identifiers
- IUPAC name
- 2-[2-nitro-4-(trifluoromethyl)benzoyl]cyclohexane-1,3-dione
- InChIKey
- OUBCNLGXQFSTLU-UHFFFAOYSA-N
- SMILES
- C1CC(=O)C(C(=O)C1)C(=O)C2=C(C=C(C=C2)C(F)(F)F)[N+](=O)[O-]
- PubChem CID
- 115355
Also known as
Nitisinone · Orfadin · 2-(2-nitro-4-(trifluoromethyl)benzoyl)cyclohexane-1,3-dione · 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione · nitisinona · nitisinonum · NITYR · NTBC cpd
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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