API reference

Ofloxacin

CAS number
82419-36-1
Molecular formula
C18H20FN3O4
Molecular weight
361.4 g/mol
Ofloxacin — 2D structure
2D structure (PubChem)

About this molecule

Ofloxacin is a racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. It has a role as an antiinfective agent, an antibacterial drug, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, a topoisomerase IV inhibitor and a DNA synthesis inhibitor. It is a racemate, a quinolone antibiotic and a fluoroquinolone antibiotic. It contains a dextrofloxacin and a levofloxacin.

Source: ChEBI, via PubChem.

Identifiers

IUPAC name
7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
InChIKey
GSDSWSVVBLHKDQ-UHFFFAOYSA-N
SMILES
CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O
Other CAS numbers recorded
83380-47-6
PubChem CID
4583

Also known as

ofloxacin · Floxin · Ofloxacine · Tarivid · Ocuflox · Ofloxacino · Visiren · Ofloxacinum

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