API reference

Olmesartan medoxomil

CAS number
144689-63-4
Molecular formula
C29H30N6O6
Molecular weight
558.6 g/mol
Olmesartan medoxomil — 2D structure
2D structure (PubChem)

About this molecule

Olmesartan Medoxomil is a synthetic imidazole derivative prodrug with an antihypertensive property. Upon hydrolysis, olmesartan medoxomil is converted to olmesartan. Olmesartan selectively binds to the angiotensin type 1 (AT1) receptor of angiotensin II in vascular smooth muscle and adrenal gland, thereby competing angiotensin II binding to the receptor. This prevents angiotensin II-induced vasoconstriction and decreases aldosterone production, thereby preventing aldosterone-stimulated sodium retention and potassium excretion.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
InChIKey
UQGKUQLKSCSZGY-UHFFFAOYSA-N
SMILES
CCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)OCC5=C(OC(=O)O5)C)C(C)(C)O
PubChem CID
130881

Also known as

Olmesartan medoxomil · Benicar · Olmetec · CS-866 · Cs 866 · CS866 · Medoxomil, Olmesartan · TRIBENZOR COMPONENT OLMESARTAN MEDOXOMIL

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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