API reference

OLOPATADINE HCl

CAS number
140462-76-6
Molecular formula
C21H24ClNO3
Molecular weight
373.9 g/mol
OLOPATADINE HCl — 2D structure
2D structure (PubChem)

About this molecule

Olopatadine Hydrochloride is the hydrochloride salt form of olopatadine, a dual action selective histamine H1 receptor antagonist and mast cell stabilizer with anti-allergic activity. Olopatadine stabilizes mast cells and prevents histamine release from mast cells. In addition, this agent also blocks histamine H1 receptors, thereby preventing histamine from binding to these receptors. Both actions prevent the effects of histamine on capillaries, bronchial smooth muscle, and gastrointestinal (GI) smooth muscle, including histamine-induced vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of GI smooth muscle. This drug also prevents histamine-induced pain and itching of mucous membranes.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
2-[(11Z)-11-[3-(dimethylamino)propylidene]-6H-benzo[c][1]benzoxepin-2-yl]acetic acid;hydrochloride
InChIKey
HVRLZEKDTUEKQH-NOILCQHBSA-N
SMILES
CN(C)CC/C=C\1/C2=CC=CC=C2COC3=C1C=C(C=C3)CC(=O)O.Cl
PubChem CID
5282402

Also known as

OLOPATADINE HYDROCHLORIDE · OLOPATADINE HCl · Pataday · Allelock · Patanase · Pazeo · Olopatadine (as hydrochloride) · Retaine Allergy

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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