API reference
Omeprazole magnesium
- CAS number
- 95382-33-5
- Molecular formula
- C34H36MgN6O6S2
- Molecular weight
- 713.1 g/mol
About this molecule
Omeprazole Magnesium is the magnesium salt form of a benzimidazole with selective and irreversible proton pump inhibitor activity. In the acidic compartment of parietal cells, omeprazole is protonated and converted into the active achiral sulfenamide; the active sulfenamide forms one or more covalent disulfide bonds with the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting its activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production. H+/K+ ATPase is an integral membrane protein of the gastric parietal cell.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- magnesium bis(5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]benzimidazol-1-ide)
- InChIKey
- KWORUUGOSLYAGD-UHFFFAOYSA-N
- SMILES
- CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.[Mg+2]
- PubChem CID
- 130564
Also known as
Omeprazole magnesium · Prilosec OTC · H 168/68 magnesium · Omeprazole (as magnesium) · H-168/68 MAGNESIUM · omeprazole magnesium salt · TALICIA COMPONENT OMEPRAZOLE MAGNESIUM · AMAZON BASIC CARE OMEPRAZOLE
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