API reference
ONDANSETRON HCl
- CAS number
- 99614-01-4
- Molecular formula
- C18H20ClN3O
- Molecular weight
- 329.8 g/mol
About this molecule
Ondansetron Hydrochloride is the hydrochloride salt of the racemic form of ondansetron, a carbazole derivative and a selective, competitive serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist with antiemetic activity. Although its mechanism of action has not been fully characterized, ondansetron appears to competitively block the action of serotonin at 5HT3 receptors peripherally in the gastrointestinal tract as well as centrally in the area postrema of the CNS, where the chemoreceptor trigger zone (CTZ) for vomiting is located, resulting in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one;hydrochloride
- InChIKey
- MKBLHFILKIKSQM-UHFFFAOYSA-N
- SMILES
- CC1=NC=CN1CC2CCC3=C(C2=O)C4=CC=CC=C4N3C.Cl
- PubChem CID
- 68647
Also known as
ONDANSETRON HYDROCHLORIDE · ONDANSETRON HCl · Zophren · Ondansetron HCl dihydrate · ZOFRAN PRESERVATIVE FREE · SN 307 · Zofran and dextrose in plastic container · Ondansetron hydrochloride preservative free
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