API reference

Paroxetine mesylate

CAS number
217797-14-3
Molecular formula
C20H24FNO6S
Molecular weight
425.5 g/mol
Paroxetine mesylate — 2D structure
2D structure (PubChem)

About this molecule

Paroxetine Mesylate is the mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties. Paroxetine binds to the pre-synaptic serotonin transporter complex resulting in negative allosteric modulation of the complex, thereby blocking reuptake of serotonin by the pre-synaptic transporter. Inhibition of serotonin recycling enhances serotonergic function through serotonin accumulation in the synaptic cleft, which resulting in long-term desensitization and downregulation of 5HT1 (serotonin) receptors and leading to symptomatic relief of depressive illness.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine;methanesulfonic acid
InChIKey
SHIJTGJXUHTGGZ-RVXRQPKJSA-N
SMILES
CS(=O)(=O)O.C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4
PubChem CID
9845306

Also known as

Paroxetine Mesylate · Paroxetine Mesilate · POT.mes · Paroxetine methanesulfonate · Brisdelle · Mesafem · Pexeva · Paroxetine methanesulphonate

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