API reference
Paroxetine mesylate
- CAS number
- 217797-14-3
- Molecular formula
- C20H24FNO6S
- Molecular weight
- 425.5 g/mol

About this molecule
Paroxetine Mesylate is the mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties. Paroxetine binds to the pre-synaptic serotonin transporter complex resulting in negative allosteric modulation of the complex, thereby blocking reuptake of serotonin by the pre-synaptic transporter. Inhibition of serotonin recycling enhances serotonergic function through serotonin accumulation in the synaptic cleft, which resulting in long-term desensitization and downregulation of 5HT1 (serotonin) receptors and leading to symptomatic relief of depressive illness.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine;methanesulfonic acid
- InChIKey
- SHIJTGJXUHTGGZ-RVXRQPKJSA-N
- SMILES
- CS(=O)(=O)O.C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4
- PubChem CID
- 9845306
Also known as
Paroxetine Mesylate · Paroxetine Mesilate · POT.mes · Paroxetine methanesulfonate · Brisdelle · Mesafem · Pexeva · Paroxetine methanesulphonate
Related entries in the range
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