API reference
PAZOPANIB HCl
- CAS number
- 635702-64-6
- Molecular formula
- C21H24ClN7O2S
- Molecular weight
- 474 g/mol
About this molecule
Pazopanib Hydrochloride is the hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR)-1, -2 and -3, c-kit and platelet derived growth factor receptor (PDGF-R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;hydrochloride
- InChIKey
- MQHIQUBXFFAOMK-UHFFFAOYSA-N
- SMILES
- CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
- PubChem CID
- 11525740
Also known as
Pazopanib hydrochloride · pazopanib HCl · pazopanib monohydrochloride · Pazopanib (as hydrochloride) · PAZOPANIB HYDROCHLORIDE (MART.) · Votrient · Pazopanib (Hydrochloride) · Armala
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