API reference
Pentoxifylline
- CAS number
- 6493-05-6
- Molecular formula
- C13H18N4O3
- Molecular weight
- 278.31 g/mol
About this molecule
Pentoxifylline is a methylxanthine derivative with hemorrheologic and immunomodulating properties. Pentoxifylline inhibits phosphodiesterase, resulting in increased levels of cyclic adenosine monophosphate (cAMP) in erythrocytes, endothelium, and the surrounding tissues. This leads to vasodilation, improves erythrocyte flexibility, and enhances blood flow. In addition, the increased level of cAMP in platelets inhibits platelet aggregation, which may contribute to a reduction in blood viscosity. This agent also inhibits production of tumor necrosis factor-alpha and interferon-gamma, while it induces Th2-like (T-helper 2) cytokine production, thereby inhibiting Th1-mediated (T-helper 1) inflammatory and autoimmune responses.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 3,7-dimethyl-1-(5-oxohexyl)purine-2,6-dione
- InChIKey
- BYPFEZZEUUWMEJ-UHFFFAOYSA-N
- SMILES
- CC(=O)CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C
- PubChem CID
- 4740
Also known as
pentoxifylline · Trental · Oxpentifylline · Pentoxil · Pentoxyphylline · Pentoxiphyllin · 1-(5-Oxohexyl)theobromine · Pentoxifilina
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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