API reference
Phenelzine sulfate
- CAS number
- 156-51-4
- Molecular formula
- C8H14N2O4S
- Molecular weight
- 234.28 g/mol
About this molecule
Phenelzine Sulfate is a hydrazine derivative and a potent non-selective monoamine oxidase (MAO) inhibitor with anxiolytic and antidepressant properties. Phenelzine sulfate irreversibly binds to MAO, thereby blocking the oxidative deamination of monoamines resulting in an increased concentration of biogenic amines and a concurrent decrease in catabolism of monoamine neurotransmitters, norepinephrine and serotonin, in the brain. In addition, through its primary metabolite phenylethylidenehyrazine (PEH), phenelzine causes elevated GABA levels in the caudate-putamen and nucleus accumbens thereby exerting its anxiolytic effects.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 2-phenylethylhydrazine;sulfuric acid
- InChIKey
- RXBKMJIPNDOHFR-UHFFFAOYSA-N
- SMILES
- C1=CC=C(C=C1)CCNN.OS(=O)(=O)O
- PubChem CID
- 61100
Also known as
Phenelzine sulfate · Phenelzine sulphate · Alazine · Phenelzine acid sulfate · Hydrazine, (2-phenylethyl)-, sulfate (1:1) · Phenethylhydrazine sulfate (1:1) · 2-Phenylethylhydrazine sulphate · 2-Phenylethylhydrazine hydrogen sulphate
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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