API reference
Pheniramine maleate
- CAS number
- 132-20-7
- Molecular formula
- C20H24N2O4
- Molecular weight
- 356.4 g/mol
About this molecule
Pheniramine Maleate is the maleate salt form of pheniramine, an alkylamine derivative with antihistaminic and vasodilatory properties. Pheniramine maleate binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of endothelium-derived relaxing factor, nitric oxide. Subsequent lack of activation of guanylyl cyclase through nitric oxide results in decreased cyclic GMP (cGMP) levels, thereby inhibiting constriction of smooth muscle tissue, and decreased capillary permeability and histamine-activated allergic reactions.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (Z)-but-2-enedioic acid;N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine
- InChIKey
- SSOXZAQUVINQSA-BTJKTKAUSA-N
- SMILES
- CN(C)CCC(C1=CC=CC=C1)C2=CC=CC=N2.C(=C\C(=O)O)\C(=O)O
- PubChem CID
- 5282139
Also known as
PHENIRAMINE MALEATE · Inhiston · Trimetose · Daneral · Trimeton · Naphcon a · Pheniramine hydrogen maleate · Antolozine
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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