API reference
PHENOXYBENZAMINE HCl
- CAS number
- 63-92-3
- Molecular formula
- C18H23Cl2NO
- Molecular weight
- 340.3 g/mol
About this molecule
Phenoxybenzamine Hydrochloride is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. Reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors which enhances norepinephrine release. Phenoxybenzamine is reasonably anticipated to be a human carcinogen.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-amine;hydrochloride
- InChIKey
- VBCPVIWPDJVHAN-UHFFFAOYSA-N
- SMILES
- CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2.Cl
- PubChem CID
- 5284441
Also known as
Phenoxybenzamine hydrochloride · Phenoxybenzamine Hcl · Dibenzyline chloride · Dibenzyline hydrochloride · Bensylyt NEN · Phenoxybenzamine chloride · Dibenzylin · N-2-Phenoxyisopropyl-N-benzyl-chloroethylamine hydrochloride
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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