API reference

Phentolamine mesilate

CAS number
65-28-1
Molecular formula
C18H23N3O4S
Molecular weight
377.5 g/mol
Phentolamine mesilate — 2D structure
2D structure (PubChem)

About this molecule

Phentolamine Mesylate is the mesylate salt of a synthetic imidazoline with alpha-adrenergic antagonist activity. As a competitive alpha-adrenergic antagonist, phentolamine binds to alpha-1 and alpha-2 receptors, resulting in a decrease in peripheral vascular resistance and vasodilatation. This agent also may block 5-hydroxytryptamine (5-HT) receptors and stimulate release of histamine from mast cells.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid
InChIKey
OGIYDFVHFQEFKQ-UHFFFAOYSA-N
SMILES
CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.CS(=O)(=O)O
PubChem CID
91430

Also known as

Phentolamine mesylate · phentolamine mesilate · Phentolamine methanesulfonate · OraVerse · Mesylate phentolamine · RYZUMVI · NV-101 · Mesilate, Phentolamine

Related entries in the range

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