API reference

PILOCARPINE HCl

CAS number
54-71-7
Molecular formula
C11H17ClN2O2
Molecular weight
244.72 g/mol
PILOCARPINE HCl — 2D structure
2D structure (PubChem)

About this molecule

Pilocarpine Hydrochloride is the hydrochloride salt of a natural alkaloid extracted from plants of the genus Pilocarpus with cholinergic agonist activity. As a cholinergic parasympathomimetic agent, pilocarpine predominantly binds to muscarinic receptors, thereby inducing exocrine gland secretion and stimulating smooth muscle in the bronchi, urinary tract, biliary tract, and intestinal tract. When applied topically to the eye, this agent stimulates the sphincter pupillae to contract, resulting in miosis; stimulates the ciliary muscle to contract, resulting in spasm of accomodation; and may cause a transitory rise in intraocular pressure followed by a more persistent fall due to opening of the trabecular meshwork and an increase in the outflow of aqueous humor.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one;hydrochloride
InChIKey
RNAICSBVACLLGM-GNAZCLTHSA-N
SMILES
CC[C@H]1[C@H](COC1=O)CC2=CN=CN2C.Cl
PubChem CID
5909

Also known as

Pilocarpine hydrochloride · Pilocarpine HCl · Salagen · Sno pilo · Pilocarpine monohydrochloride · Isopto carpine · Vistacarpin N · PILOPINE HS

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