API reference

PIOGLITAZONE HCl

CAS number
112529-15-4
Molecular formula
C19H21ClN2O3S
Molecular weight
392.9 g/mol
PIOGLITAZONE HCl — 2D structure
2D structure (PubChem)

About this molecule

Pioglitazone Hydrochloride is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation. (NCI05)

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydrochloride
InChIKey
GHUUBYQTCDQWRA-UHFFFAOYSA-N
SMILES
CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3.Cl
Other CAS numbers recorded
127676-30-6
PubChem CID
60560

Also known as

pioglitazone hydrochloride · Pioglitazone HCl · Piomed · Diabiom · Glidipion · Glizofar · Pioglitazone (as hydrochloride) · STR-001

Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.

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