API reference
Piperaquine
- CAS number
- 4085-31-8
- Molecular formula
- C29H32Cl2N6
- Molecular weight
- 535.5 g/mol
About this molecule
Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China. Its use declined in the 1980's as piperaquine resistant strains of *Plasmodium falciparum* appeared and artemisinin derivatives became available. It has come back into use in combination with the artemisinin derivative [DB11638] as part of the combination product Eurartesim. Eurartesim was first authorized for market by the European Medicines Agency in October 2011.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- 7-chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl]piperazin-1-yl]quinoline
- InChIKey
- UCRHFBCYFMIWHC-UHFFFAOYSA-N
- SMILES
- C1CN(CCN1CCCN2CCN(CC2)C3=C4C=CC(=CC4=NC=C3)Cl)C5=C6C=CC(=CC6=NC=C5)Cl
- PubChem CID
- 122262
Also known as
piperaquine · Piperaquinoline · 1,3-Bis(4-(7-chloroquinolin-4-yl)piperazin-1-yl)propane · 1,3-bis(1-(7-chloro-4'-quinolyl)-4'-piperazinyl)propane · Piperaquine (USAN) · C29H32Cl2N6 · Piperaquine Base · piperaquine-phosphate
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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