API reference
Pirfenidone
- CAS number
- 53179-13-8
- Molecular formula
- C12H11NO
- Molecular weight
- 185.22 g/mol
About this molecule
Pirfenidone is a synthetic pyridone drug. It is an antifibrotic agent with anti-inflammatory and antioxidant properties that is used to treat idiopathic pulmonary fibrosis (IPF), which is a chronic, progressive form of interstitial pneumonia. While its mechanism of action is not yet fully understood, pirfenidone is proposed to primarily regulate tumor necrosis factor (TNF) pathways and modulate cellular oxidation. The FDA first approved pirfenidone alongside [nintedanib] as one of the first drugs to treat IPF.
Source: DrugBank, via PubChem.
Identifiers
- IUPAC name
- 5-methyl-1-phenylpyridin-2-one
- InChIKey
- ISWRGOKTTBVCFA-UHFFFAOYSA-N
- SMILES
- CC1=CN(C(=O)C=C1)C2=CC=CC=C2
- PubChem CID
- 40632
Also known as
Esbriet · Pirespa · AMR-69 · Pirfenidona · Pirfenidonum · 5-methyl-1-phenylpyridin-2-one · 2(1H)-Pyridinone, 5-methyl-1-phenyl- · 5-Methyl-1-phenyl-2(1H)-pyridone
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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