API reference
Polidocanol
- CAS number
- 3055-99-0
- Molecular formula
- C30H62O10
- Molecular weight
- 582.8 g/mol
About this molecule
Polidocanol is an alkyl polyglycol ether of lauryl alcohol with sclerosing and potential antineoplastic activities. Upon intralesional administration, polidocanol induces endothelial cell injury by disrupting calcium signaling and nitric oxide pathways. Following endothelial damage, platelets aggregate at the site of injury and attach to the venous wall, resulting in a dense network of platelets, cellular debris, and fibrin that occludes the vessel. Inducing endothelial cell damage within melanoma metastases may incite an antitumor response in untreated bystander lesions and inhibit the growth of in transit metastases and other cutaneous lesions.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 2-[2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
- InChIKey
- ONJQDTZCDSESIW-UHFFFAOYSA-N
- SMILES
- CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
- Other CAS numbers recorded
- 9043-30-5
- PubChem CID
- 656641
Also known as
Polidocanol · Nonaethylene glycol monododecyl ether · Asclera · Aethoxy-sklerol · nonaethylene glycol monolauryl ether · VARITHENA · PEG-9 lauryl ether · Macrogol 9 lauryl ether
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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