API reference
Pomalidomide
- CAS number
- 19171-19-8
- Molecular formula
- C13H11N3O4
- Molecular weight
- 273.24 g/mol
About this molecule
Pomalidomide is an orally bioavailable derivative of thalidomide with potential immunomodulating, antiangiogenic and antineoplastic activities. Although its exact mechanism of action has yet to be fully elucidated, pomalidomide appears to inhibit TNF-alpha production, enhance the activity of T cells and natural killer (NK) cells and enhance antibody-dependent cellular cytotoxicity (ADCC). In addition, pomalidomide may inhibit tumor angiogenesis, promote cell cycle arrest in susceptible tumor cell populations, and stimulate erythropoeisis.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
- InChIKey
- UVSMNLNDYGZFPF-UHFFFAOYSA-N
- SMILES
- C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N
- Other CAS numbers recorded
- 443919-33-3
- PubChem CID
- 134780
Also known as
Pomalidomide · Actimid · Pomalyst · Imnovid · 4-Aminothalidomide · 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione · IMID-3 · 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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