API reference

PRAMOXINE HCl

CAS number
637-58-1
Molecular formula
C17H28ClNO3
Molecular weight
329.9 g/mol
PRAMOXINE HCl — 2D structure
2D structure (PubChem)

About this molecule

Pramocaine Hydrochloride is the hydrochloride salt form of pramoxine, a morpholine derivative with local anesthetic property. Pramocaine hydrochloride decreases the permeability of the neuronal membrane to sodium ions by reversibly binding to and inhibiting voltage-gated sodium channels. This results in stabilization of the membrane and, thereby inhibiting the ionic fluxes required for membrane depolarization, hence resulting in the failure to initiate a propagated action potential and subsequent conduction blockade.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
4-[3-(4-butoxyphenoxy)propyl]morpholine;hydrochloride
InChIKey
SYCBXBCPLUFJID-UHFFFAOYSA-N
SMILES
CCCCOC1=CC=C(C=C1)OCCCN2CCOCC2.Cl
PubChem CID
73957

Also known as

Pramoxine hydrochloride · Pramoxine HCl · Pramocaine hydrochloride · Tronothane · Walgreen Anti-Itch · 4-(3-(p-Butoxyphenoxy)propyl)morpholine hydrochloride · Pramoxine hydrochloride (USP) · CVS Health Maximum Strength Feminine

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