API reference
Probenecid
- CAS number
- 57-66-9
- Molecular formula
- C13H19NO4S
- Molecular weight
- 285.36 g/mol
About this molecule
Probenecid is a benzoic acid derivative with antihyperuricemic property. Probenecid competitively inhibits the active reabsorption of urate at the proximal tubule in the kidney thereby increasing urinary excretion of uric acid and lowering serum urate concentrations. This prevents urate deposition and promotes resolution of existing urate deposits. In addition, probenecid modulates the transport of organic acids and acidic drugs at the proximal and distal renal tubule, thereby increasing the drug serum concentration.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 4-(dipropylsulfamoyl)benzoic acid
- InChIKey
- DBABZHXKTCFAPX-UHFFFAOYSA-N
- SMILES
- CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(=O)O
- PubChem CID
- 4911
Also known as
probenecid · 4-(Dipropylsulfamoyl)benzoic acid · Benemid · Probenecid acid · Probecid · Benecid · Apurina · Benuryl
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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