API reference
PROCAINAMIDE HCl
- CAS number
- 614-39-1
- Molecular formula
- C13H22ClN3O
- Molecular weight
- 271.78 g/mol
About this molecule
Procainamide Hydrochloride is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog of procaine. Procainamide hydrochloride reversibly binds to and blocks activated (open) voltage-gated sodium channels, thereby blocks the influx of sodium ions into the cell, which leads to an increase in threshold for excitation and inhibit depolarization during phase 0 of the action potential. In addition, the effective refractory period (ERP), action potential duration (APD), and ERP/APD ratios are increased, resulting in decreased impulse conduction velocity. The lasting action potential may also be due to blockage of outward K+ currents. The result is a decrease in automaticity, increase in refractory period and slowing of impulse conduction.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 4-amino-N-[2-(diethylamino)ethyl]benzamide;hydrochloride
- InChIKey
- ABTXGJFUQRCPNH-UHFFFAOYSA-N
- SMILES
- CCN(CC)CCNC(=O)C1=CC=C(C=C1)N.Cl
- Other CAS numbers recorded
- 7699-39-0
- PubChem CID
- 66068
Also known as
procainamide hydrochloride · Procainamide Hcl · Procanbid · Procapan · Procan SR · Pronestyl-Sr · Amidoprocaine · Cardiorytmin
Chemical data on this page is drawn from PubChem (National Library of Medicine) and is provided for identification only. Hanpars does not hold stock of every substance listed; availability, grade, documentation and regulatory status are confirmed per enquiry.
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