API reference
Prochlorperazine maleate
- CAS number
- 84-02-6
- Molecular formula
- C28H32ClN3O8S
- Molecular weight
- 606.1 g/mol
About this molecule
Prochlorperazine Maleate is the maleate salt form of prochlorperazine, a synthetic, piperazine phenothiazine derivative with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine binds to and blocks the postsynaptic dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. Prochlorperazine maleate also blocks anticholinergic and alpha-adrenergic receptors. Its antagonistic actions on the alpha-1 adrenergic receptors results in sedation, muscle relaxation, and hypotension.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- bis((Z)-but-2-enedioic acid);2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
- InChIKey
- DSKIOWHQLUWFLG-SPIKMXEPSA-N
- SMILES
- CN1CCN(CC1)CCCN2C3=C(SC4=CC=CC=C24)C=CC(=C3)Cl.C(=C\C(=O)O)\C(=O)O.C(=C\C(=O)O)\C(=O)O
- PubChem CID
- 5281032
Also known as
Prochlorperazine dimaleate · Prochlorperazine maleate · Proclorperazine maleate · Prochlorperazinu dimaleat · Prochlorperazine bimaleate · Proziere · Prochlorperazine hydrogen maleate · Prochloroproazine hydrogen maleate
Related entries in the range
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