API reference

Progesterone

CAS number
57-83-0
Molecular formula
C21H30O2
Molecular weight
314.5 g/mol
Progesterone — 2D structure
2D structure (PubChem)

About this molecule

Therapeutic Progesterone is the therapeutic form of the naturally occurring hormone progesterone. Progesterone binds to the progesterone receptor, resulting in dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors. This agent exerts inhibitory effects on estrogens by decreasing the number of estrogen receptors and increasing its metabolism to inactive metabolites. Progesterone induces secretory changes in the endometrium, decreases uterine contractility during pregnancy, and maintains pregnancy.

Source: NCI Thesaurus (NCIt), via PubChem.

Identifiers

IUPAC name
(8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
InChIKey
RJKFOVLPORLFTN-LEKSSAKUSA-N
SMILES
CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C
Other CAS numbers recorded
137940-28-4
PubChem CID
5994

Also known as

progesterone · Pregn-4-ene-3,20-dione · Agolutin · Progestin · Crinone · Utrogestan · Luteol · Cyclogest

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